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(Updated 4:30 p.m. Wed., March 26) In the last six months alone, Missouri hospitals have eliminated nearly 1,000 jobs, imposed hiring freezes affecting...

Missouri and Illinois are producing less carbon pollution than a decade ago but are still emitting more than many other states, according to the U.S....

In a major shakeup, Lewis D'Vorkin steps down as editor in chief of the newspaper. He will be replaced by veteran Chicago journalist Jim Kirk.

Members of the Buffalo community grieving loved ones organized an evening vigil that honored the shooting victims while combining stirring gospel music and calls to action.

As the Writers Guild of America began its first strike in 15 years, union members let loose with quips to studio executives, as they picketed outside companies like Netflix, Sony and NBCUniversal.

Mayor Rahm Emanuel has chosen a new interim police superintendent. Officer Eddie Johnson, currently chief of patrol, will take over what many see as the toughest police chief job in the country.

This was a big year for corporate mergers, with $3 trillion worth of deals announced worldwide. Analysts say the strong acquisitive trend is expected to continue into next year.

President Trump on Thursday evening reiterates his interest in denying the U.S. Postal Service funds, which he says would kneecap efforts to expand mail-in voting.

President Trump released his long-awaited plan to direct $1.5 trillion toward upgrading U.S. roads, bridges, airports and other public works projects.

Also: Funeral today for slain Virginia Tech police officer; Russian billionaire says he'll challenge Putin; Occupy protesters aim to close West Coast ports.