The Department of Social Services says it aims to accommodate Missourians who experience acute medical events or travel for treatment using other, mandatory exemptions in federal law

Rules on licensing and ownership of cannabis facilities could change in Missouri soon.

Residents can respond online and will see new questions in specific sections.

Community members discussed where to relocate Katy Station, the old railroad depot.

Cooper's Landing Riverside Resort and Marina in Columbia is anticipating rising floodwaters on Sunday night and early Monday morning.

The Protect College Sports Act is touted as a fix for a number of ills plaguing college athletics in an age of skyrocketing costs at the Division I level. But there are many more Division II and Division III schools that would also be impacted.

A 7-year-old girl was injured riding her new bike. A stranger came to her rescue and gifted her an origami crane with a hidden message she would only discover years later.

It's likely you've already chewed and swallowed some tasty morsel today. But when did that ability emerge? New evidence points to at least the middle Jurassic, back when dinosaurs still reigned.

The Pentagon says Nidal Hasan will be executed by firing squad in December at Fort Hood, where he killed 13 people in 2009. The announcement came days after a botched lethal injection in Tennessee.

An analysis shows a rise in emergency room visits correlates to temperature increases. The highest numbers of visits occurred when severe daytime heat was combined with unusually warm nighttime temperatures.

A class action suit alleges the company did not fully disclose financial relationships with businesses tied to co-founders.

There is now greater access to naloxone, a medication that can reverse opioid overdoses, in Boonville and Cooper County.

Guest host Camryn Faith interviews her own mother about The COMO 411, a local digital media company founded in 2022 to tell the stories of people, places, and things that make Columbia, Missouri a great place to live. From humble beginnings to a growing platform with members, events, and reach beyond city limits, find out how The COMO 411 is amplifying authentic community voices and what exciting expansion is coming next! October 2, 2026

The Centers for Disease Control and Prevention issued an official health alert due to an increase of reports in human exposure to rabid or possibly rabid animals, according to the CDC’s website.

Dyed diesel is typically illegal for highway use, but the governor's executive order makes an exception for vehicles operating on state highways for agricultural purposes.